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IL-1R3 blockade broadly attenuates the functions of six members of the IL-1 family, revealing their contribution to models of disease.
Højen, Jesper Falkesgaard; Kristensen, Marie Louise Vindvad; McKee, Amy S; Wade, Megan Taylor; Azam, Tania; Lunding, Lars P; de Graaf, Dennis M; Swartzwelter, Benjamin J; Wegmann, Michael; Tolstrup, Martin; Beckman, Karsten; Fujita, Mayumi; Fischer, Stephan; Dinarello, Charles A.
Affiliation
  • Højen JF; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
  • Kristensen MLV; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • McKee AS; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Wade MT; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Azam T; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Lunding LP; Department of Microbiology and Immunology, University of Colorado Denver, Aurora, CO, USA.
  • de Graaf DM; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Swartzwelter BJ; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Wegmann M; Division of Asthma Exacerbation & Regulation, Priority Area Asthma and Allergy, Leibniz Lung Center Borstel, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Borstel, Germany.
  • Tolstrup M; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Beckman K; Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Fujita M; Department of Medicine, University of Colorado Denver, Aurora, CO, USA.
  • Fischer S; Division of Asthma Exacerbation & Regulation, Priority Area Asthma and Allergy, Leibniz Lung Center Borstel, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Borstel, Germany.
  • Dinarello CA; Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Nat Immunol ; 20(9): 1138-1149, 2019 09.
Article in En | MEDLINE | ID: mdl-31427775
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritonitis / Pneumonia / Psoriasis / Antibodies, Blocking / Interleukin-1 Receptor Accessory Protein / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peritonitis / Pneumonia / Psoriasis / Antibodies, Blocking / Interleukin-1 Receptor Accessory Protein / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Document type: Article Affiliation country: