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Biologic Agents and Secondary Immune Deficiency.
Axelrod, Heather; Adams, Matthew.
Affiliation
  • Axelrod H; Department of Pediatrics (PGY3), Children's Hospital of Michigan, Detroit, MI, USA.
  • Adams M; Division of Pediatric Rheumatology, Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, 3950 Beaubien Boulevard, Detroit, MI 48201, USA. Electronic address: madams3@dmc.org.
Pediatr Clin North Am ; 66(5): 1007-1020, 2019 10.
Article in En | MEDLINE | ID: mdl-31466676
ABSTRACT
Biologics are protein-based pharmaceuticals derived from living organisms or their proteins. We discuss the mechanism of action for currently approved biologics and a give summary of the studies on immune suppression from biologics. Most of these studies have been conducted with rheumatology patients, and many in adults. Their relevance for children is explored and existing gaps in data for children are highlighted.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Factors / Antibodies, Monoclonal, Humanized / Immune Tolerance / Immunologic Deficiency Syndromes Limits: Child / Humans Language: En Journal: Pediatr Clin North Am Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Factors / Antibodies, Monoclonal, Humanized / Immune Tolerance / Immunologic Deficiency Syndromes Limits: Child / Humans Language: En Journal: Pediatr Clin North Am Year: 2019 Document type: Article Affiliation country: