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Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS-Dependent Pancreatic Ductal Adenocarcinoma.
Mottini, Carla; Tomihara, Hideo; Carrella, Diego; Lamolinara, Alessia; Iezzi, Manuela; Huang, Justin K; Amoreo, Carla A; Buglioni, Simonetta; Manni, Isabella; Robinson, Frederick S; Minelli, Rosalba; Kang, Ya'an; Fleming, Jason B; Kim, Michael P; Bristow, Christopher A; Trisciuoglio, Daniela; Iuliano, Antonella; Del Bufalo, Donatella; Di Bernardo, Diego; Melisi, Davide; Draetta, Giulio F; Ciliberto, Gennaro; Carugo, Alessandro; Cardone, Luca.
Affiliation
  • Mottini C; Department of Tumor Immunology and Immunotherapy, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Tomihara H; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Carrella D; Telethon Institute of Genetics and Medicine (TIGEM), Napoli, Italy.
  • Lamolinara A; Department of Medicine and Aging Science, Center for Advanced Studies and Technology (CAST), G. D'Annunzio University, Chieti-Pescara, Italy.
  • Iezzi M; Department of Medicine and Aging Science, Center for Advanced Studies and Technology (CAST), G. D'Annunzio University, Chieti-Pescara, Italy.
  • Huang JK; Department of Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Amoreo CA; Department of Pathology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Buglioni S; Department of Pathology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Manni I; Animal Facility (SAFU), IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Robinson FS; Department of Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Minelli R; Department of Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Kang Y; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Fleming JB; Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, Florida.
  • Kim MP; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Bristow CA; Department of Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Trisciuoglio D; Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Iuliano A; Institute of Molecular Biology and Pathology, National Research Council, Rome, Italy.
  • Del Bufalo D; Telethon Institute of Genetics and Medicine (TIGEM), Napoli, Italy.
  • Di Bernardo D; Preclinical Models and New Therapeutic Agents Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.
  • Melisi D; Telethon Institute of Genetics and Medicine (TIGEM), Napoli, Italy.
  • Draetta GF; Department of Medicine, University of Verona, Verona, Italy.
  • Ciliberto G; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Carugo A; Department of Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Cardone L; IRCCS Regina Elena National Cancer Institute, Rome, Italy.
Cancer Res ; 79(21): 5612-5625, 2019 Nov 01.
Article in En | MEDLINE | ID: mdl-31492820
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Proto-Oncogene Proteins p21(ras) / Carcinoma, Pancreatic Ductal / Decitabine Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Adenocarcinoma / Proto-Oncogene Proteins p21(ras) / Carcinoma, Pancreatic Ductal / Decitabine Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Cancer Res Year: 2019 Document type: Article Affiliation country: