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Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay.
Shi, Liu; Westwood, Sarah; Baird, Alison L; Winchester, Laura; Dobricic, Valerija; Kilpert, Fabian; Hong, Shengjun; Franke, Andre; Hye, Abdul; Ashton, Nicholas J; Morgan, Angharad R; Bos, Isabelle; Vos, Stephanie J B; Buckley, Noel J; Kate, Mara Ten; Scheltens, Philip; Vandenberghe, Rik; Gabel, Silvy; Meersmans, Karen; Engelborghs, Sebastiaan; De Roeck, Ellen E; Sleegers, Kristel; Frisoni, Giovanni B; Blin, Olivier; Richardson, Jill C; Bordet, Régis; Molinuevo, José L; Rami, Lorena; Wallin, Anders; Kettunen, Petronella; Tsolaki, Magda; Verhey, Frans; Lleó, Alberto; Alcolea, Daniel; Popp, Julius; Peyratout, Gwendoline; Martinez-Lage, Pablo; Tainta, Mikel; Johannsen, Peter; Teunissen, Charlotte E; Freund-Levi, Yvonne; Frölich, Lutz; Legido-Quigley, Cristina; Barkhof, Frederik; Blennow, Kaj; Zetterberg, Henrik; Baker, Susan; Morgan, B Paul; Streffer, Johannes; Visser, Pieter Jelle.
Affiliation
  • Shi L; Department of Psychiatry, University of Oxford, Oxford, UK. Electronic address: liu.shi@psych.ox.ac.uk.
  • Westwood S; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Baird AL; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Winchester L; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Dobricic V; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany.
  • Kilpert F; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany.
  • Hong S; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany.
  • Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany.
  • Hye A; Maurice Wohl Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK.
  • Ashton NJ; Maurice Wohl Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, Kings College London, London, UK; Department of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden; Wallenberg Centre for Molecular & Translational Medicine, University of Gothenburg,
  • Morgan AR; Dementia Research Institute Cardiff, Cardiff University, Cardiff, UK.
  • Bos I; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Centrum Limburg, Maastricht University, Maastricht, the Netherlands.
  • Vos SJB; Alzheimer Center, VU University Medical Center, Amsterdam, the Netherlands.
  • Buckley NJ; Department of Psychiatry, University of Oxford, Oxford, UK.
  • Kate MT; Alzheimer Center, VU University Medical Center, Amsterdam, the Netherlands.
  • Scheltens P; Alzheimer Center, VU University Medical Center, Amsterdam, the Netherlands.
  • Vandenberghe R; University Hospital Leuven, Leuven, Belgium.
  • Gabel S; University Hospital Leuven, Leuven, Belgium; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Belgium.
  • Meersmans K; University Hospital Leuven, Leuven, Belgium; Laboratory for Cognitive Neurology, Department of Neurosciences, KU Leuven, Belgium.
  • Engelborghs S; Center for Neurosciences, Vrije Universiteit Brussel (VUB), Brussels, Belgium; Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium; Department of Neurology, VUB University Hospital Brusse
  • De Roeck EE; Center for Neurosciences, Vrije Universiteit Brussel (VUB), Brussels, Belgium; Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Sleegers K; Institute Born-Bunge, University of Antwerp, Antwerp, Belgium; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Edegem, Belgium.
  • Frisoni GB; University of Geneva, Geneva, Switzerland; IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Blin O; AIX Marseille University, INS, Ap-hm, Marseille, France.
  • Richardson JC; Neurosciences Therapeutic Area, GlaxoSmithKline R&D, Stevenage, UK.
  • Bordet R; University of Lille, Inserm, CHU Lille, Lille, France.
  • Molinuevo JL; Alzheimer's disease & other cognitive disorders unit, Hopsital Clínic-IDIBAPS, Barcelona, Spain; Barcelona Beta Brain Research Center, Universitat Pompeu Fabra, Barcelona, Spain.
  • Rami L; Barcelona Beta Brain Research Center, Universitat Pompeu Fabra, Barcelona, Spain.
  • Wallin A; Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
  • Kettunen P; Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
  • Tsolaki M; 1st Department of Neurology, AHEPA University Hospital, Makedonia, Thessaloniki, Greece.
  • Verhey F; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Centrum Limburg, Maastricht University, Maastricht, the Netherlands.
  • Lleó A; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Alcolea D; Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Popp J; University Hospital of Lausanne, Lausanne, Switzerland; Geriatric Psychiatry, Department of Mental Health and Psychiatry, Geneva University Hospitals, Geneva, Switzerland.
  • Peyratout G; University Hospital of Lausanne, Lausanne, Switzerland.
  • Martinez-Lage P; CITA-Alzheimer Foundation, San Sebastian, Spain.
  • Tainta M; CITA-Alzheimer Foundation, San Sebastian, Spain.
  • Johannsen P; Danish Dementia Research Centre, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
  • Teunissen CE; Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Amsterdam University Medical Centers, Vrije Universiteit, Amsterdam, The Netherlands.
  • Freund-Levi Y; Department of Neurobiology, Caring Sciences and Society (NVS), Division of Clinical Geriatrics, Karolinska Institutet, and Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden; Department of Psychiatry in Region Örebro County and School of Medical Sciences, Fa
  • Frölich L; Department of Geriatric Psychiatry, Zentralinstitut für Seelische Gesundheit, University of Heidelberg, Mannheim, Germany.
  • Legido-Quigley C; Kings College London, London, UK; The Systems Medicine Group, Steno Diabetes Center, Gentofte, Denmark.
  • Barkhof F; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherland; UCL Institutes of Neurology and Healthcare Engineering, London, UK.
  • Blennow K; Department of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.
  • Zetterberg H; Department of Psychiatry and Neurochemistry, University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; UK Dementia Research Institute at UCL, London, UK; Department of Neurodegenerative Disease, UCL Institute of Neurology, London
  • Baker S; Janssen R&D, Titusville, NJ, USA.
  • Morgan BP; Dementia Research Institute Cardiff, Cardiff University, Cardiff, UK.
  • Streffer J; Reference Center for Biological Markers of Dementia (BIODEM), University of Antwerp, Antwerp, Belgium; Janssen R&D, LLC, Beerse, Belgium.
  • Visser PJ; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Centrum Limburg, Maastricht University, Maastricht, the Netherlands; Alzheimer Center, VU University Medical Center, Amsterdam, the Netherlands; Department of Neurobiology, Care Sciences and Society, D
Alzheimers Dement ; 15(11): 1478-1488, 2019 11.
Article in En | MEDLINE | ID: mdl-31495601
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Biomarkers / Proteomics / Alzheimer Disease / Amyloid Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Alzheimers Dement Year: 2019 Document type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Biomarkers / Proteomics / Alzheimer Disease / Amyloid Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Alzheimers Dement Year: 2019 Document type: Article