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Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive?
de Korte, Tessa; Katili, Puspita A; Mohd Yusof, Nurul A N; van Meer, Berend J; Saleem, Umber; Burton, Francis L; Smith, Godfrey L; Clements, Peter; Mummery, Christine L; Eschenhagen, Thomas; Hansen, Arne; Denning, Chris.
Affiliation
  • de Korte T; Ncardia, 2333 BD Leiden, The Netherlands.
  • Katili PA; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD Leiden, The Netherlands.
  • Mohd Yusof NAN; Department of Stem Cell Biology, University of Nottingham, NG7 2RD Nottingham, United Kingdom; email: chris.denning@nottingham.ac.uk.
  • van Meer BJ; Department of Stem Cell Biology, University of Nottingham, NG7 2RD Nottingham, United Kingdom; email: chris.denning@nottingham.ac.uk.
  • Saleem U; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD Leiden, The Netherlands.
  • Burton FL; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany.
  • Smith GL; Institute of Cardiovascular and Medical Sciences, University of Glasgow, G12 8QQ Glasgow, United Kingdom.
  • Clements P; Institute of Cardiovascular and Medical Sciences, University of Glasgow, G12 8QQ Glasgow, United Kingdom.
  • Mummery CL; David Jack Centre for Research & Development, GlaxoSmithKline, SG12 0DP Hertfordshire, United Kingdom.
  • Eschenhagen T; Department of Anatomy and Embryology, Leiden University Medical Center, 2333 ZD Leiden, The Netherlands.
  • Hansen A; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany.
  • Denning C; Department of Experimental Pharmacology and Toxicology, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany.
Annu Rev Pharmacol Toxicol ; 60: 529-551, 2020 01 06.
Article in En | MEDLINE | ID: mdl-31506008
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Cardiac / Drug Discovery / Cardiotoxicity Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Annu Rev Pharmacol Toxicol Year: 2020 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Cardiac / Drug Discovery / Cardiotoxicity Type of study: Guideline / Prognostic_studies Limits: Animals / Humans Language: En Journal: Annu Rev Pharmacol Toxicol Year: 2020 Document type: Article Affiliation country: