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Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell Death.
Froeling, Fieke E M; Swamynathan, Manojit Mosur; Deschênes, Astrid; Chio, Iok In Christine; Brosnan, Erin; Yao, Melissa A; Alagesan, Priya; Lucito, Matthew; Li, Juying; Chang, An-Yun; Trotman, Lloyd C; Belleau, Pascal; Park, Youngkyu; Rogoff, Harry A; Watson, James D; Tuveson, David A.
Affiliation
  • Froeling FEM; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Swamynathan MM; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Deschênes A; Northwell Cancer Institute, Lake Success, New York.
  • Chio IIC; Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
  • Brosnan E; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Yao MA; Graduate Program in Molecular and Cellular Biology, Stony Brook University, Stony Brook, New York.
  • Alagesan P; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Lucito M; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Li J; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Chang AY; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Trotman LC; Institute for Cancer Genetics, Columbia University, New York, New York.
  • Belleau P; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Park Y; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Rogoff HA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
  • Watson JD; Lustgarten Foundation Pancreatic Cancer Research Laboratory, Cold Spring Harbor, New York.
  • Tuveson DA; Icahn School of Medicine at Mount Sinai, New York, New York.
Clin Cancer Res ; 25(23): 7162-7174, 2019 12 01.
Article in En | MEDLINE | ID: mdl-31527169
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Benzofurans / Naphthoquinones / NAD(P)H Dehydrogenase (Quinone) / Reactive Oxygen Species / Apoptosis / STAT3 Transcription Factor Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Document type: Article Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Benzofurans / Naphthoquinones / NAD(P)H Dehydrogenase (Quinone) / Reactive Oxygen Species / Apoptosis / STAT3 Transcription Factor Limits: Humans Language: En Journal: Clin Cancer Res Journal subject: NEOPLASIAS Year: 2019 Document type: Article Country of publication: