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Radioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signalling.
Qureishi, Ali; Rieunier, Guillaume; Shah, Ketan A; Aleksic, Tamara; Winter, Stuart C; Møller, Henrik; Macaulay, Valentine M.
Affiliation
  • Qureishi A; Department of Oncology, University of Oxford, Oxford, UK.
  • Rieunier G; Nuffield Department of Surgery, University of Oxford and Department of Head and Neck Surgery, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.
  • Shah KA; Department of Oncology, University of Oxford, Oxford, UK.
  • Aleksic T; Department of Cellular Pathology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • Winter SC; Department of Oncology, University of Oxford, Oxford, UK.
  • Møller H; Nuffield Department of Surgery, University of Oxford and Department of Head and Neck Surgery, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK.
  • Macaulay VM; School of Cancer and Pharmaceutical Sciences, King's College London, London, UK.
Clin Otolaryngol ; 44(6): 1026-1036, 2019 11.
Article in En | MEDLINE | ID: mdl-31536667

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Somatomedins / Carcinoma, Squamous Cell / Signal Transduction / Laryngeal Neoplasms / Receptor, IGF Type 1 / Epidermal Growth Factor Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Otolaryngol Journal subject: OTORRINOLARINGOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Somatomedins / Carcinoma, Squamous Cell / Signal Transduction / Laryngeal Neoplasms / Receptor, IGF Type 1 / Epidermal Growth Factor Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Clin Otolaryngol Journal subject: OTORRINOLARINGOLOGIA Year: 2019 Document type: Article Affiliation country: Country of publication: