Highly divergent cattle hepacivirus N in Southern Brazil.
Arch Virol
; 164(12): 3133-3136, 2019 Dec.
Article
in En
| MEDLINE
| ID: mdl-31563979
ABSTRACT
The genus Hepacivirus includes 14 species (Hepacivirus A-N). In this study, we determined a partial genome sequence of a highly divergent bovine hepacivirus (hepacivirus N, HNV) isolate from cattle in Southern Brazil. Previously described HNV isolates have shared 80-99.7% nucleotide sequence identity in the NS3 coding region. However, the sequence determined in this study had 72.6% to 73.8% nucleotide sequence identity to known HNV NS3 sequences. This high divergence could be seen in a phylogenetic tree, suggesting that it represents a new genotype of HNV. These data expand our knowledge concerning the genetic variability and evolution of hepaciviruses.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Cattle Diseases
/
Hepatitis C
/
Hepacivirus
/
Evolution, Molecular
Limits:
Animals
Country/Region as subject:
America do sul
/
Brasil
Language:
En
Journal:
Arch Virol
Year:
2019
Document type:
Article
Affiliation country: