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Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display.
Vragniau, Charles; Bufton, Joshua C; Garzoni, Frédéric; Stermann, Emilie; Rabi, Fruzsina; Terrat, Céline; Guidetti, Mélanie; Josserand, Véronique; Williams, Matt; Woods, Christopher J; Viedma, Gerardo; Bates, Phil; Verrier, Bernard; Chaperot, Laurence; Schaffitzel, Christiane; Berger, Imre; Fender, Pascal.
Affiliation
  • Vragniau C; Institut de Biologie Structurale (IBS), Université Grenoble Alpes, CNRS, CEA, 71 Avenue des Martyrs, 38042 Grenoble, France.
  • Bufton JC; Bristol Research Centre for Synthetic Biology BrisSynBio, School of Biochemistry, University of Bristol, 1 Tankard's Close, Bristol BS8 1TD, UK.
  • Garzoni F; Imophoron Ltd., Unit DX, St. Philips Central, Albert Road, Bristol BS2 OXJ, UK.
  • Stermann E; Institut de Biologie Structurale (IBS), Université Grenoble Alpes, CNRS, CEA, 71 Avenue des Martyrs, 38042 Grenoble, France.
  • Rabi F; Bristol Research Centre for Synthetic Biology BrisSynBio, School of Biochemistry, University of Bristol, 1 Tankard's Close, Bristol BS8 1TD, UK.
  • Terrat C; Laboratoire de Biologie Tissulaire et d'Ingénierie Thérapeutique (LBTI), UMR 5305, Université Lyon 1, CNRS, Institut de Biologie et Chimie des Protéines (IBCP), Lyon, France.
  • Guidetti M; Cancer Target and Experimental Therapeutics, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, 38700 Grenoble, France.
  • Josserand V; Cancer Target and Experimental Therapeutics, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, 38700 Grenoble, France.
  • Williams M; Advanced Computing Research Centre, University of Bristol, 31 Great George Street, Bristol BS1 5QD, UK.
  • Woods CJ; Advanced Computing Research Centre, University of Bristol, 31 Great George Street, Bristol BS1 5QD, UK.
  • Viedma G; Oracle Cloud Development Centre, Tower Wharf, Cheese Lane, Bristol BS2 2JJ, UK.
  • Bates P; Oracle Cloud Development Centre, Tower Wharf, Cheese Lane, Bristol BS2 2JJ, UK.
  • Verrier B; Laboratoire de Biologie Tissulaire et d'Ingénierie Thérapeutique (LBTI), UMR 5305, Université Lyon 1, CNRS, Institut de Biologie et Chimie des Protéines (IBCP), Lyon, France.
  • Chaperot L; Immunobiology and Immunotherapy in Chronic Diseases, Institute for Advanced Biosciences, INSERM U1209, CNRS UMR5309, Université Grenoble Alpes, Etablissement Français du Sang-Rhone-Alpes, 38700 Grenoble, France.
  • Schaffitzel C; Bristol Research Centre for Synthetic Biology BrisSynBio, School of Biochemistry, University of Bristol, 1 Tankard's Close, Bristol BS8 1TD, UK.
  • Berger I; Bristol Research Centre for Synthetic Biology BrisSynBio, School of Biochemistry, University of Bristol, 1 Tankard's Close, Bristol BS8 1TD, UK.
  • Fender P; Max Planck-Bristol Centre for Minimal Biology, Cantock's Close, Bristol BS8 1TS, UK.
Sci Adv ; 5(9): eaaw2853, 2019 09.
Article in En | MEDLINE | ID: mdl-31620562
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Vaccines, Synthetic / Adenoviridae / Epitope Mapping / Epitopes Type of study: Etiology_studies Limits: Humans Language: En Journal: Sci Adv Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Vaccines, Synthetic / Adenoviridae / Epitope Mapping / Epitopes Type of study: Etiology_studies Limits: Humans Language: En Journal: Sci Adv Year: 2019 Document type: Article Affiliation country: