Novel fluorescein- and pyridine-conjugated schiff base probes for the recyclable real-time determination of Ce3+ and F.
Methods Appl Fluoresc
; 8(1): 015002, 2019 Nov 13.
Article
in En
| MEDLINE
| ID: mdl-31622961
ABSTRACT
The effect of aminopyridines substituted at different positions on the fluorescence properties deserves to be studied. Since 2-aminopyridyl-based probes have been reported, the effects of 3-aminopyridine and 4-aminopyridine on the performance of fluorescein probes were discussed in here. Two Schiff base fluorescein probes FN-1, FN-2 were designed and synthesized. Among them, since the ligand shows a highly selective and sensitive response to metal charge transfer (LMCT), the fluorescence of FN-1 can be quenched by Ce3+ ions in PBS buffer. At the same time, a specific precipitation reaction between Ce3+ and F- releases the free probe to restore the fluorescence of FN-1. Therefore, FN-1 can be used for the recyclable 'ON-OFF-ON' detection of Ce3+and F-. The detection limits for Ce3+and F- are 4.48 µM and 11.58 µM in concentration range of 0-50 µM and 0-150 µM. However, due to the para position of N and amino groups on 4-aminopyridine, the spatial structure of FN-2 cannot be complexed with ions, resulting in poor selectivity. Polyvinylidene fluoride (PVDF) membrane containing FN-1 were prepared for the real-time qualitative detection of Ce3+and F- in real water samples. FN-1 exhibits high water solubility and biocompatibility and has been successfully applied to biological imaging in vascular smooth muscle cells (VSMCs).
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pyridines
/
Cerium
/
Fluorescein
/
Fluorescent Dyes
/
Fluorides
Type of study:
Qualitative_research
Language:
En
Journal:
Methods Appl Fluoresc
Year:
2019
Document type:
Article