Your browser doesn't support javascript.
loading
Evolution of IFN subgroups in bony fish - 1:Group I-III IFN exist in early ray-finned fish, with group II IFN subgroups present in the Holostean spotted gar, Lepisosteus oculatus.
Liu, Fuguo; Bols, Niels C; Pham, Phuc H; Secombes, Christopher J; Zou, Jun.
Affiliation
  • Liu F; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK.
  • Bols NC; Department of Biology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
  • Pham PH; Department of Biology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
  • Secombes CJ; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK.
  • Zou J; Scottish Fish Immunology Research Centre, University of Aberdeen, Aberdeen, AB24 2TZ, Scotland, UK; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai, 201306, China; Laboratory for Marine Biology and Biotechnology,
Fish Shellfish Immunol ; 95: 163-170, 2019 Dec.
Article in En | MEDLINE | ID: mdl-31626921
ABSTRACT
The present study helps clarify when the fish type I IFN groups/subgroups evolved, by examination of the IFN genes present in the Holostean spotted gar, Lepisosteus oculatus, in relation to the IFN genes present in the Chondrostea (sturgeon). It confirms that all three IFN groups (I-III), and group II subgroups, existed prior to the appearance of teleost fish. Preliminary expression analysis in a gar cell line (GARL) suggests these IFN genes will have a role in antiviral defence in Holostean fish, in that they are induced by poly(IC). A refined model of IFN evolution within the actinopterygian fish is proposed.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skates, Fish / Interferons / Evolution, Molecular / Fishes Limits: Animals Language: En Journal: Fish Shellfish Immunol Journal subject: BIOLOGIA / MEDICINA VETERINARIA Year: 2019 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skates, Fish / Interferons / Evolution, Molecular / Fishes Limits: Animals Language: En Journal: Fish Shellfish Immunol Journal subject: BIOLOGIA / MEDICINA VETERINARIA Year: 2019 Document type: Article Affiliation country: