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DNA methylation of indoleamine 2,3-dioxygenase 1 (IDO1) in head and neck squamous cell carcinomas correlates with IDO1 expression, HPV status, patients' survival, immune cell infiltrates, mutational load, and interferon γ signature.
Sailer, Verena; Sailer, Ulrike; Bawden, Emma Grace; Zarbl, Romina; Wiek, Constanze; Vogt, Timo J; Dietrich, Joern; Loick, Sophia; Grünwald, Ingela; Toma, Marieta; Golletz, Carsten; Gerstner, Andreas; Kristiansen, Glen; Bootz, Friedrich; Scheckenbach, Kathrin; Landsberg, Jennifer; Dietrich, Dimo.
Affiliation
  • Sailer V; Pathology of the University Hospital Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.
  • Sailer U; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Bawden EG; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
  • Zarbl R; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Wiek C; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Düsseldorf, Düsseldorf, Germany.
  • Vogt TJ; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Dietrich J; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Loick S; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Grünwald I; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Toma M; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
  • Golletz C; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
  • Gerstner A; Department of Otolaryngology, Head and Neck Surgery, Municipal Hospital Braunschweig, Braunschweig, Germany.
  • Kristiansen G; Institute of Pathology, University Hospital Bonn, Bonn, Germany.
  • Bootz F; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
  • Scheckenbach K; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Düsseldorf, Düsseldorf, Germany.
  • Landsberg J; Department of Dermatology and Allergy, University Hospital Bonn, Bonn, Germany.
  • Dietrich D; Department of Otolaryngology, Head and Neck Surgery, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany. Electronic address: dimo.dietrich@gmail.com.
EBioMedicine ; 48: 341-352, 2019 Oct.
Article in En | MEDLINE | ID: mdl-31628024

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Papillomaviridae / DNA Methylation / Papillomavirus Infections / Indoleamine-Pyrrole 2,3,-Dioxygenase / Squamous Cell Carcinoma of Head and Neck Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: EBioMedicine Year: 2019 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Papillomaviridae / DNA Methylation / Papillomavirus Infections / Indoleamine-Pyrrole 2,3,-Dioxygenase / Squamous Cell Carcinoma of Head and Neck Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Journal: EBioMedicine Year: 2019 Document type: Article Affiliation country: