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Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer.
Osei-Amponsa, Vasty; Buckwalter, Jenna M; Shuman, Lauren; Zheng, Zongyu; Yamashita, Hironobu; Walter, Vonn; Wildermuth, Thomas; Ellis-Mohl, Justine; Liu, Chang; Warrick, Joshua I; Shantz, Lisa M; Feehan, Robert P; Al-Ahmadie, Hikmat; Mendelsohn, Cathy; Raman, Jay D; Kaestner, Klaus H; Wu, Xue-Ru; DeGraff, David J.
Affiliation
  • Osei-Amponsa V; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Buckwalter JM; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Shuman L; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Zheng Z; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Yamashita H; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Walter V; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Wildermuth T; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Ellis-Mohl J; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Liu C; Department of Public Health Sciences, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Warrick JI; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Shantz LM; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Feehan RP; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Al-Ahmadie H; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Mendelsohn C; Department of Urology, Columbia University, New York, NY, USA.
  • Raman JD; Department of Pathology and Laboratory Medicine, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Kaestner KH; Department of Surgery, Division of Urology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • Wu XR; Department of Cellular and Molecular Physiology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
  • DeGraff DJ; Department of Cellular and Molecular Physiology, The Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Oncogene ; 39(6): 1302-1317, 2020 02.
Article in En | MEDLINE | ID: mdl-31636388
Subject(s)
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Carcinoma, Squamous Cell / Cell Differentiation / DNA Methylation / Loss of Heterozygosity / PTEN Phosphohydrolase / Hepatocyte Nuclear Factor 3-alpha Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Carcinoma, Squamous Cell / Cell Differentiation / DNA Methylation / Loss of Heterozygosity / PTEN Phosphohydrolase / Hepatocyte Nuclear Factor 3-alpha Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2020 Document type: Article Affiliation country: Country of publication: