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Cardiac safety assessment with motion field imaging analysis of human iPS cell-derived cardiomyocytes is improved by an integrated evaluation with cardiac ion channel profiling.
Isobe, Takehito; Honda, Masaki; Komatsu, Ryuichi; Tabo, Mitsuyasu.
Affiliation
  • Isobe T; Research Division, Chugai Pharmaceutical Co., Ltd.
  • Honda M; Translational Research Division, Chugai Pharmaceutical Co., Ltd.
  • Komatsu R; Research Division, Chugai Pharmaceutical Co., Ltd.
  • Tabo M; Research Division, Chugai Pharmaceutical Co., Ltd.
J Toxicol Sci ; 44(12): 859-870, 2019.
Article in En | MEDLINE | ID: mdl-31813905
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Action Potentials / Myocytes, Cardiac / Induced Pluripotent Stem Cells / Ion Channels / Myocardial Contraction Limits: Animals / Humans / Male Language: En Journal: J Toxicol Sci Year: 2019 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Action Potentials / Myocytes, Cardiac / Induced Pluripotent Stem Cells / Ion Channels / Myocardial Contraction Limits: Animals / Humans / Male Language: En Journal: J Toxicol Sci Year: 2019 Document type: Article