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Screening of periodontopathic bacteria in Italian patients affected by periodontitis.
Scapoli, L; Arcuri, C; D'Orto, O; Bolzoni, A; Lagana, F; Carinci, F.
Affiliation
  • Scapoli L; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
  • Arcuri C; Department of Clinical Sciences and Translational Medicine, University of Tor Vergata, Rome, Italy.
  • D'Orto O; Maxillofacial and Dental Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Bolzoni A; Maxillofacial and Dental Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
  • Lagana F; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
  • Carinci F; Maxillofacial and Dental Unit, IRCCS Cà Ospedale Policlinico San Martino, Genova, Italy.
J Biol Regul Homeost Agents ; 33(6 Suppl. 1): 15-20. DENTAL SUPPLEMENT, 2019.
Article in En | MEDLINE | ID: mdl-31828989
ABSTRACT
Periodontal disease (PD) is among the most common infectious diseases in the world, caused by pathogenic bacteria that trigger innate, inflammatory, and adaptive immune responses, leading to the destruction of supporting periodontal tissues and, if untreated, tooth loss. This study included 3593 patients, of them 1963 had a complete dataset and thus were analysed 1088 (55%) were from Northern Italy, 749 (38%) from Central and 126 (7%) from Southern. Aggregatibacter actinomycetemcomitans, Porphyromonas gengivalis, Treponema denticola, and Tannerella forsythia, Campylobacter rectus, Fusobacterium nucleatum, and total bacterial load were investigated. There was a significant difference in geographic distribution as regard A. actinomycetemcomitans (p<0.001), C. rectus (p<0.001), F. nucleatum (p<0.001) and total bacterial load (p<0.001). No differences were detected as regard gender, whereas a significant higher F. nucleatum load was observed in younger patients.
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Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Observational_studies / Screening_studies Language: En Journal: J Biol Regul Homeost Agents Journal subject: BIOLOGIA / BIOQUIMICA Year: 2019 Document type: Article Affiliation country:
Search on Google
Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Observational_studies / Screening_studies Language: En Journal: J Biol Regul Homeost Agents Journal subject: BIOLOGIA / BIOQUIMICA Year: 2019 Document type: Article Affiliation country: