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DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes.
Van Rompay, Koen K A; Keesler, Rebekah I; Ardeshir, Amir; Watanabe, Jennifer; Usachenko, Jodie; Singapuri, Anil; Cruzen, Christina; Bliss-Moreau, Eliza; Murphy, Ashley M; Yee, JoAnn L; Webster, Helen; Dennis, Maria; Singh, Tulika; Heimsath, Holly; Lemos, Danilo; Stuart, Jackson; Morabito, Kaitlyn M; Foreman, Bryant M; Burgomaster, Katherine E; Noe, Amy T; Dowd, Kimberly A; Ball, Erin; Woolard, Kevin; Presicce, Pietro; Kallapur, Suhas G; Permar, Sallie R; Foulds, Kathryn E; Coffey, Lark L; Pierson, Theodore C; Graham, Barney S.
Affiliation
  • Van Rompay KKA; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA. kkvanrompay@ucdavis.edu bgraham@nih.gov.
  • Keesler RI; Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA.
  • Ardeshir A; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Watanabe J; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Usachenko J; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Singapuri A; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Cruzen C; Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA.
  • Bliss-Moreau E; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Murphy AM; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Yee JL; Department of Psychology, University of California, Davis, Davis, CA 95616, USA.
  • Webster H; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Dennis M; Department of Psychology, University of California, Davis, Davis, CA 95616, USA.
  • Singh T; California National Primate Research Center, University of California, Davis, Davis, CA 95616, USA.
  • Heimsath H; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Lemos D; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Stuart J; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Morabito KM; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Foreman BM; Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA.
  • Burgomaster KE; Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA.
  • Noe AT; Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA.
  • Dowd KA; Laboratory of Viral Diseases, NIAID, NIH, Bethesda, MD 20892, USA.
  • Ball E; Laboratory of Viral Diseases, NIAID, NIH, Bethesda, MD 20892, USA.
  • Woolard K; Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA.
  • Presicce P; Laboratory of Viral Diseases, NIAID, NIH, Bethesda, MD 20892, USA.
  • Kallapur SG; Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA.
  • Permar SR; Department of Pathology, Microbiology and Immunology, University of California, Davis, Davis, CA 95616, USA.
  • Foulds KE; Divisions of Neonatology and Developmental Biology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Coffey LL; Divisions of Neonatology and Developmental Biology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
  • Pierson TC; Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA.
  • Graham BS; Vaccine Research Center, NIAID, NIH, Bethesda, MD 20892, USA.
Sci Transl Med ; 11(523)2019 12 18.
Article in En | MEDLINE | ID: mdl-31852797
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccination / Vaccines, DNA / Zika Virus Infection Limits: Animals / Pregnancy Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vaccination / Vaccines, DNA / Zika Virus Infection Limits: Animals / Pregnancy Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2019 Document type: Article