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PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
Corbett, Grant T; Wang, Zemin; Hong, Wei; Colom-Cadena, Marti; Rose, Jamie; Liao, Meichen; Asfaw, Adhana; Hall, Tia C; Ding, Lai; DeSousa, Alexandra; Frosch, Matthew P; Collinge, John; Harris, David A; Perkinton, Michael S; Spires-Jones, Tara L; Young-Pearse, Tracy L; Billinton, Andrew; Walsh, Dominic M.
Affiliation
  • Corbett GT; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Wang Z; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Hong W; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Colom-Cadena M; Centre for Discovery Brain Sciences and UK Dementia Research Institute, University of Edinburgh, Edinburgh, EH89JZ, UK.
  • Rose J; Centre for Discovery Brain Sciences and UK Dementia Research Institute, University of Edinburgh, Edinburgh, EH89JZ, UK.
  • Liao M; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Asfaw A; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Hall TC; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Ding L; Program for Interdisciplinary Neuroscience, Brigham and Women's Hospital, Boston, MA, 02115, USA.
  • DeSousa A; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Frosch MP; Massachusetts General Institute for Neurodegenerative Disease, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA.
  • Collinge J; MRC Prion Unit at UCL, UCL Institute of Prion Diseases, National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG, UK.
  • Harris DA; Department of Biochemistry, Boston University School of Medicine, Boston, MA, 02118, USA.
  • Perkinton MS; Neuroscience, IMED Biotechnology Unit, AstraZeneca, Cambridge, CB21 6GH, UK.
  • Spires-Jones TL; Centre for Discovery Brain Sciences and UK Dementia Research Institute, University of Edinburgh, Edinburgh, EH89JZ, UK.
  • Young-Pearse TL; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA.
  • Billinton A; Neuroscience, IMED Biotechnology Unit, AstraZeneca, Cambridge, CB21 6GH, UK.
  • Walsh DM; Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Hale Building for Transformative Medicine, 60 Fenwood Road, Boston, MA, 02115, USA. dwalsh3@bwh.harvard.edu.
Acta Neuropathol ; 139(3): 503-526, 2020 03.
Article in En | MEDLINE | ID: mdl-31853635

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / Amyloid beta-Peptides / Tau Proteins / Neurodegenerative Diseases / Alpha-Synuclein / Neurons Limits: Animals / Humans Language: En Journal: Acta Neuropathol Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prions / Amyloid beta-Peptides / Tau Proteins / Neurodegenerative Diseases / Alpha-Synuclein / Neurons Limits: Animals / Humans Language: En Journal: Acta Neuropathol Year: 2020 Document type: Article Affiliation country: Country of publication: