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A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides.
Wolska, Anna; Lo, Larry; Sviridov, Denis O; Pourmousa, Mohsen; Pryor, Milton; Ghosh, Soumitra S; Kakkar, Rahul; Davidson, Michael; Wilson, Sierra; Pastor, Richard W; Goldberg, Ira J; Basu, Debapriya; Drake, Steven K; Cougnoux, Antony; Wu, Ming Jing; Neher, Saskia B; Freeman, Lita A; Tang, Jingrong; Amar, Marcelo; Devalaraja, Matt; Remaley, Alan T.
Affiliation
  • Wolska A; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. aremaley1@nhlbi.nih.gov anna.wolska@nih.gov matt@corvidiatx.com.
  • Lo L; Corvidia Therapeutics Inc., Waltham, MA 02451, USA.
  • Sviridov DO; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Pourmousa M; Laboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Pryor M; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Ghosh SS; Corvidia Therapeutics Inc., Waltham, MA 02451, USA.
  • Kakkar R; Corvidia Therapeutics Inc., Waltham, MA 02451, USA.
  • Davidson M; Corvidia Therapeutics Inc., Waltham, MA 02451, USA.
  • Wilson S; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Pastor RW; Laboratory of Computational Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Goldberg IJ; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  • Basu D; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
  • Drake SK; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.
  • Cougnoux A; Division of Translational Medicine, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
  • Wu MJ; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Neher SB; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Freeman LA; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Tang J; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Amar M; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Devalaraja M; Corvidia Therapeutics Inc., Waltham, MA 02451, USA. aremaley1@nhlbi.nih.gov anna.wolska@nih.gov matt@corvidiatx.com.
  • Remaley AT; Lipoprotein Metabolism Laboratory, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA. aremaley1@nhlbi.nih.gov anna.wolska@nih.gov matt@corvidiatx.com.
Sci Transl Med ; 12(528)2020 01 29.
Article in En | MEDLINE | ID: mdl-31996466
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Triglycerides / Apolipoprotein C-II / Apolipoprotein C-III Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptides / Triglycerides / Apolipoprotein C-II / Apolipoprotein C-III Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article