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Pik3ca mutations significantly enhance the growth of SHH medulloblastoma and lead to metastatic tumour growth in a novel mouse model.
Niesen, Judith; Ohli, Jasmin; Sedlacik, Jan; Dührsen, Lasse; Hellwig, Malte; Spohn, Michael; Holsten, Till; Schüller, Ulrich.
Affiliation
  • Niesen J; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Research Institute Children's Cancer Centre Hamburg, Hamburg, Germany.
  • Ohli J; Centre for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany.
  • Sedlacik J; Department of Neuroradiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Dührsen L; Department of Neurosurgery, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
  • Hellwig M; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Research Institute Children's Cancer Centre Hamburg, Hamburg, Germany.
  • Spohn M; Research Institute Children's Cancer Centre Hamburg, Hamburg, Germany.
  • Holsten T; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Research Institute Children's Cancer Centre Hamburg, Hamburg, Germany.
  • Schüller U; Department of Pediatric Hematology and Oncology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany; Research Institute Children's Cancer Centre Hamburg, Hamburg, Germany; Institute of Neuropathology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. Electronic address: u.sch
Cancer Lett ; 477: 10-18, 2020 05 01.
Article in En | MEDLINE | ID: mdl-32112900
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebellar Neoplasms / Class I Phosphatidylinositol 3-Kinases / Medulloblastoma / Mutation Limits: Animals / Humans Language: En Journal: Cancer Lett Year: 2020 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebellar Neoplasms / Class I Phosphatidylinositol 3-Kinases / Medulloblastoma / Mutation Limits: Animals / Humans Language: En Journal: Cancer Lett Year: 2020 Document type: Article Affiliation country: