[Stimulating effect of water-soluble fraction from brown algae Fucus vesiculosus extract on cell proliferation in tissue culture of young and old rats.]
Adv Gerontol
; 32(6): 990-995, 2019.
Article
in Ru
| MEDLINE
| ID: mdl-32160439
ABSTRACT
The influence of water-soluble fraction F-55 of brown algae extract Fucus vesiculosus on the development of organotypic tissue culture of different genesis, originating from three germ leaves in young and old rats was studied. The preparation F-55 has a stimulating effect on the processes of cell proliferation in the tissues of ecto-, ento- and mesodermal genesis (cerebral cortex, myocardium, spleen and liver), by regulating the processes of cell proliferation and apoptosis. The revealed strengthening of regeneration processes in explants from both young and old rats under the influence of F-55 preparation in the range of ultra-low concentrations of 10-100 ng/ml can serve as a basis for the creation of new medicinal cytoprotective substances that allow to enhance cell regeneration in various tissues in pathological conditions, including those associated with age.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Plant Extracts
/
Fucus
/
Cell Proliferation
Limits:
Animals
Language:
Ru
Journal:
Adv Gerontol
Journal subject:
GERIATRIA
Year:
2019
Document type:
Article