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A multimodal approach to identify clinically relevant biomarkers to comprehensively monitor disease progression in a mouse model of pediatric neurodegenerative disease.
Johnson, Tyler B; Brudvig, Jon J; Lehtimäki, Kimmo K; Cain, Jacob T; White, Katherine A; Bragge, Timo; Rytkönen, Jussi; Huhtala, Tuulia; Timm, Derek; Vihma, Maria; Puoliväli, Jukka T; Poutiainen, Pekka; Nurmi, Antti; Weimer, Jill M.
Affiliation
  • Johnson TB; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
  • Brudvig JJ; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
  • Lehtimäki KK; Discovery Research Services, Charles River, Kuopio, Finland.
  • Cain JT; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
  • White KA; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
  • Bragge T; Discovery Research Services, Charles River, Kuopio, Finland.
  • Rytkönen J; Discovery Research Services, Charles River, Kuopio, Finland.
  • Huhtala T; Discovery Research Services, Charles River, Kuopio, Finland.
  • Timm D; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA.
  • Vihma M; Discovery Research Services, Charles River, Kuopio, Finland.
  • Puoliväli JT; Discovery Research Services, Charles River, Kuopio, Finland.
  • Poutiainen P; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.
  • Nurmi A; Discovery Research Services, Charles River, Kuopio, Finland. Electronic address: antti.nurmi@crl.com.
  • Weimer JM; Pediatrics and Rare Diseases Group, Sanford Research, Sioux Falls, SD, USA; Department of Pediatrics, Sanford School of Medicine at the University of South Dakota, Sioux Falls, SD, USA. Electronic address: jill.weimer@sanfordhealth.org.
Prog Neurobiol ; 189: 101789, 2020 06.
Article in En | MEDLINE | ID: mdl-32198061
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Biomarkers / Disease Progression / Gait Disorders, Neurologic / Neuronal Ceroid-Lipofuscinoses Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Prog Neurobiol Year: 2020 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Biomarkers / Disease Progression / Gait Disorders, Neurologic / Neuronal Ceroid-Lipofuscinoses Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Prog Neurobiol Year: 2020 Document type: Article Affiliation country: