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ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging.
Zhao, Jing; Zhang, Lei; Lu, Aiping; Han, Yingchao; Colangelo, Debora; Bukata, Christina; Scibetta, Alex; Yousefzadeh, Matthew J; Li, Xuesen; Gurkar, Aditi U; McGowan, Sara J; Angelini, Luise; O'Kelly, Ryan; Li, Hongshuai; Corbo, Lana; Sano, Tokio; Nick, Heather; Pola, Enrico; Pilla, Smitha P S; Ladiges, Warren C; Vo, Nam; Huard, Johnny; Niedernhofer, Laura J; Robbins, Paul D.
Affiliation
  • Zhao J; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Zhang L; Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55415, USA.
  • Lu A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Han Y; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Colangelo D; Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55415, USA.
  • Bukata C; Department of Orthopaedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • Scibetta A; Steadman Philippon Research Institute, Vail, CO 81657, USA.
  • Yousefzadeh MJ; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Li X; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Gurkar AU; Department of Orthopaedic Surgery, Catholic University of Rome School of Medicine, "A. Gemelli" University Hospital, Roma, Italy.
  • McGowan SJ; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Angelini L; Department of Orthopaedic Surgery, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
  • O'Kelly R; Steadman Philippon Research Institute, Vail, CO 81657, USA.
  • Li H; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Corbo L; Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55415, USA.
  • Sano T; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Nick H; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Pola E; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Pilla SPS; Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55415, USA.
  • Ladiges WC; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Vo N; Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55415, USA.
  • Huard J; Department of Molecular Medicine and the Center on Aging, Scripps Research, Jupiter, FL 33458, USA.
  • Niedernhofer LJ; Institute on the Biology of Aging and Metabolism and Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, MN 55415, USA.
  • Robbins PD; Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
Aging (Albany NY) ; 12(6): 4688-4710, 2020 03 22.
Article in En | MEDLINE | ID: mdl-32201398
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / DNA Damage / Aging / NF-kappa B / Cellular Senescence / Ataxia Telangiectasia Mutated Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / DNA Damage / Aging / NF-kappa B / Cellular Senescence / Ataxia Telangiectasia Mutated Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2020 Document type: Article Affiliation country: Country of publication: