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Disruption of cholinergic neurotransmission, within a cognitive challenge paradigm, is indicative of Aß-related cognitive impairment in preclinical Alzheimer's disease after a 27-month delay interval.
Alber, Jessica; Maruff, Paul; Santos, Cláudia Y; Ott, Brian R; Salloway, Stephen P; Yoo, Don C; Noto, Richard B; Thompson, Louisa I; Goldfarb, Danielle; Arthur, Edmund; Song, Alex; Snyder, Peter J.
Affiliation
  • Alber J; Department of Biological & Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 75 Lower College Road, 2nd Floor, Kingston, RI, USA.
  • Maruff P; Ryan Institute for Neuroscience, University of Rhode Island, Kingston, RI, USA.
  • Santos CY; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Ott BR; Cogstate Ltd., Melbourne, Victoria, Australia.
  • Salloway SP; The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Victoria, Australia.
  • Yoo DC; Department of Biological & Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, 75 Lower College Road, 2nd Floor, Kingston, RI, USA.
  • Noto RB; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Thompson LI; Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Goldfarb D; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Arthur E; Department of Neurology, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Song A; Department of Radiology, Warren Alpert Medical School of Brown University, Providence, RI, USA.
  • Snyder PJ; Department of Radiology, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Alzheimers Res Ther ; 12(1): 31, 2020 03 24.
Article in En | MEDLINE | ID: mdl-32209123

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease / Cognitive Dysfunction Type of study: Prognostic_studies / Screening_studies Limits: Aged / Female / Humans / Middle aged Language: En Journal: Alzheimers Res Ther Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Alzheimer Disease / Cognitive Dysfunction Type of study: Prognostic_studies / Screening_studies Limits: Aged / Female / Humans / Middle aged Language: En Journal: Alzheimers Res Ther Year: 2020 Document type: Article Affiliation country: Country of publication: