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Synthesis of novel hybrid quinolino[4,3-b][1,5]naphthyridines and quinolino[4,3-b][1,5]naphthyridin-6(5H)-one derivatives and biological evaluation as topoisomerase I inhibitors and antiproliferatives.
Martín-Encinas, Endika; Selas, Asier; Tesauro, Cinzia; Rubiales, Gloria; Knudsen, Birgitta R; Palacios, Francisco; Alonso, Concepción.
Affiliation
  • Martín-Encinas E; Departamento de Química Orgánica I, Facultad de Farmacia and Centro de Investigación Lascaray (Lascaray Research Center). Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Paseo de la Universidad 7, 01006, Vitoria-Gasteiz, Spain.
  • Selas A; Departamento de Química Orgánica I, Facultad de Farmacia and Centro de Investigación Lascaray (Lascaray Research Center). Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Paseo de la Universidad 7, 01006, Vitoria-Gasteiz, Spain; Department of Molecular Biology and Genetics and Int
  • Tesauro C; Department of Molecular Biology and Genetics and Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, 8000, Denmark.
  • Rubiales G; Departamento de Química Orgánica I, Facultad de Farmacia and Centro de Investigación Lascaray (Lascaray Research Center). Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Paseo de la Universidad 7, 01006, Vitoria-Gasteiz, Spain.
  • Knudsen BR; Department of Molecular Biology and Genetics and Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, 8000, Denmark.
  • Palacios F; Departamento de Química Orgánica I, Facultad de Farmacia and Centro de Investigación Lascaray (Lascaray Research Center). Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Paseo de la Universidad 7, 01006, Vitoria-Gasteiz, Spain. Electronic address: francisco.palacios@ehu.eus.
  • Alonso C; Departamento de Química Orgánica I, Facultad de Farmacia and Centro de Investigación Lascaray (Lascaray Research Center). Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Paseo de la Universidad 7, 01006, Vitoria-Gasteiz, Spain. Electronic address: concepcion.alonso@ehu.eus.
Eur J Med Chem ; 195: 112292, 2020 Jun 01.
Article in En | MEDLINE | ID: mdl-32279049
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / DNA Topoisomerases, Type I / Naphthyridines Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / DNA Topoisomerases, Type I / Naphthyridines Limits: Humans Language: En Journal: Eur J Med Chem Year: 2020 Document type: Article Affiliation country: Country of publication: