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A High-Throughput Cellular Screening Assay for Small-Molecule Inhibitors and Activators of Cytoplasmic Dynein-1-Based Cargo Transport.
Vincent, John; Preston, Marian; Mouchet, Elizabeth; Laugier, Nicolas; Corrigan, Adam; Boulanger, Jérôme; Brown, Dean G; Clark, Roger; Wigglesworth, Mark; Carter, Andrew P; Bullock, Simon L.
Affiliation
  • Vincent J; HTS, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Macclesfield, Cheshire, UK.
  • Preston M; HTS, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Macclesfield, Cheshire, UK.
  • Mouchet E; HTS, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Macclesfield, Cheshire, UK.
  • Laugier N; Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.
  • Corrigan A; Quantitative Biology, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Cambridge, Cambridgeshire, UK.
  • Boulanger J; Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.
  • Brown DG; Hit Discovery, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Boston, USA.
  • Clark R; Discovery Biology, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Cambridge, Cambridgeshire, UK.
  • Wigglesworth M; HTS, Discovery Sciences, Bio Pharmaceuticals R&D, AstraZeneca, Macclesfield, Cheshire, UK.
  • Carter AP; Division of Structural Studies, MRC Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.
  • Bullock SL; Division of Cell Biology, MRC Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.
SLAS Discov ; 25(9): 985-999, 2020 10.
Article in En | MEDLINE | ID: mdl-32436764
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peroxisomes / Small Molecule Libraries / Cytoplasmic Dyneins / High-Throughput Screening Assays Limits: Humans Language: En Journal: SLAS Discov Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peroxisomes / Small Molecule Libraries / Cytoplasmic Dyneins / High-Throughput Screening Assays Limits: Humans Language: En Journal: SLAS Discov Year: 2020 Document type: Article Affiliation country: Country of publication: