5' modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage.
Nucleic Acids Res
; 48(12): 6811-6823, 2020 07 09.
Article
in En
| MEDLINE
| ID: mdl-32496535
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
RNA, Guide, Kinetoplastida
/
DNA Cleavage
/
CRISPR-Cas Systems
/
R-Loop Structures
Language:
En
Journal:
Nucleic Acids Res
Year:
2020
Document type:
Article
Affiliation country: