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Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.
Michlits, Georg; Jude, Julian; Hinterndorfer, Matthias; de Almeida, Melanie; Vainorius, Gintautas; Hubmann, Maria; Neumann, Tobias; Schleiffer, Alexander; Burkard, Thomas Rainer; Fellner, Michaela; Gijsbertsen, Max; Traunbauer, Anna; Zuber, Johannes; Elling, Ulrich.
Affiliation
  • Michlits G; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Jude J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • Hinterndorfer M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • de Almeida M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • Vainorius G; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Hubmann M; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Neumann T; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • Schleiffer A; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Burkard TR; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • Fellner M; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Gijsbertsen M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • Traunbauer A; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
  • Zuber J; Institute of Molecular Biotechnology of the Austrian Academy of Science (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
  • Elling U; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Nat Methods ; 17(7): 708-716, 2020 07.
Article in En | MEDLINE | ID: mdl-32514112
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Guide, Kinetoplastida / Alleles / CRISPR-Cas Systems Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Methods Journal subject: TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: RNA, Guide, Kinetoplastida / Alleles / CRISPR-Cas Systems Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Nat Methods Journal subject: TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2020 Document type: Article Affiliation country: Country of publication: