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Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis.
Cook, Dana P; Cunha, João Paulo Monteiro Carvalho Mori; Martens, Pieter-Jan; Sassi, Gabriele; Mancarella, Francesca; Ventriglia, Giuliana; Sebastiani, Guido; Vanherwegen, An-Sofie; Atkinson, Mark A; Van Huynegem, Karolien; Steidler, Lothar; Caluwaerts, Silvia; Rottiers, Pieter; Teyton, Luc; Dotta, Francesco; Gysemans, Conny; Mathieu, Chantal.
Affiliation
  • Cook DP; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
  • Cunha JPMCM; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
  • Martens PJ; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
  • Sassi G; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
  • Mancarella F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena and Fondazione Umberto Di Mario ONLUS-Toscana Life Science Park, Siena, Italy.
  • Ventriglia G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena and Fondazione Umberto Di Mario ONLUS-Toscana Life Science Park, Siena, Italy.
  • Sebastiani G; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena and Fondazione Umberto Di Mario ONLUS-Toscana Life Science Park, Siena, Italy.
  • Vanherwegen AS; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
  • Atkinson MA; Immunology and Laboratory Medicine, Department of Pathology, College of Medicine, University of Florida Diabetes Institute, Gainesville, FL, United States.
  • Van Huynegem K; ActoBio Therapeutics™, Ghent, Belgium.
  • Steidler L; ActoBio Therapeutics™, Ghent, Belgium.
  • Caluwaerts S; ActoBio Therapeutics™, Ghent, Belgium.
  • Rottiers P; ActoBio Therapeutics™, Ghent, Belgium.
  • Teyton L; The Teyton Lab, Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA, United States.
  • Dotta F; Diabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena and Fondazione Umberto Di Mario ONLUS-Toscana Life Science Park, Siena, Italy.
  • Gysemans C; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
  • Mathieu C; Clinical and Experimental Endocrinology (CEE), Department of Chronic Diseases, Metabolism and Ageing, Campus Gasthuisberg O&N 1, Katholieke Universiteit Leuven (KU Leuven), Leuven, Belgium.
Front Immunol ; 11: 1103, 2020.
Article in En | MEDLINE | ID: mdl-32582188
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proinsulin / Interleukin-10 / CD3 Complex / Diabetes Mellitus, Type 1 / Insulin-Secreting Cells Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Front Immunol Year: 2020 Document type: Article Affiliation country:
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proinsulin / Interleukin-10 / CD3 Complex / Diabetes Mellitus, Type 1 / Insulin-Secreting Cells Type of study: Diagnostic_studies Limits: Animals / Humans Language: En Journal: Front Immunol Year: 2020 Document type: Article Affiliation country: