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Risk or Beneficial Factors Associated with Unplanned Revascularization Risk Following Percutaneous Coronary Intervention: A Large Single-Center Data.
Liu, Ru; Gao, Zhan; Gao, Li Jian; Zhao, Xue Yan; Chen, Jue; Qiao, Shu Bin; Yang, Yue Jin; Gao, Run Lin; Xu, Bo; Yuan, Jin Qing.
Affiliation
  • Liu R; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Gao Z; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Gao LJ; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Zhao XY; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Chen J; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Qiao SB; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Yang YJ; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Gao RL; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Xu B; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
  • Yuan JQ; Department of Cardiology, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China.
Biomed Environ Sci ; 33(6): 431-443, 2020 Jun 20.
Article in En | MEDLINE | ID: mdl-32641206
OBJECTIVE: To analyze factors associated with unplanned revascularization (UR) risk in patients with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI). METHODS: A total of 10,640 cases with CAD who underwent PCI were analyzed. Multivariate COX regressions and competing risk regressions were applied. RESULTS: The patients who underwent UR following PCI in 30 days, 1, and 2 years accounted for 0.3%, 6.5%, and 8.7%, respectively. After multivariate adjustment, the number of target lesions [hazard ratio ( HR) = 2.320; 95% confidence interval ( CI): 1.643-3.277; P < 0.001], time of procedure ( HR= 1.006; 95% CI: 1.001-1.010; P = 0.014), body mass index ( HR= 1.104; 95% CI: 1.006-1.210; P = 0.036), incomplete revascularization (ICR) ( HR= 2.476; 95% CI: 1.030-5.952; P = 0.043), and age ( HR = 1.037; 95% CI: 1.000-1.075; P = 0.048) were determined as independent risk factors of 30-day UR. Factors, including low-molecular-weight heparin or fondaparinux ( HR= 0.618; 95% CI: 0.531-0.719; P < 0.001), second-generation durable polymer drug-eluting stent ( HR = 0.713; 95% CI: 0.624-0.814; P < 0.001), left anterior descending artery involvement ( HR= 0.654; 95% CI: 0.530-0.807; P < 0.001), and age ( HR= 0.992; 95% CI: 0.985-0.998; P = 0.014), were independently associated with decreased two-year UR risk. While, Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery score ( HR= 1.024; 95% CI: 1.014-1.033; P < 0.001) and ICR ( HR= 1.549; 95% CI: 1.290-1.860; P < 0.001) were negatively associated with two-year UR risk. CONCLUSION: Specific factors were positively or negatively associated with short- and medium-long-term UR following PCI.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease / Percutaneous Coronary Intervention / Myocardial Revascularization Type of study: Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Biomed Environ Sci Journal subject: SAUDE AMBIENTAL Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease / Percutaneous Coronary Intervention / Myocardial Revascularization Type of study: Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Biomed Environ Sci Journal subject: SAUDE AMBIENTAL Year: 2020 Document type: Article Affiliation country: Country of publication: