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Uncoupling sodium channel dimers restores the phenotype of a pain-linked Nav 1.7 channel mutation.
Rühlmann, Annika H; Körner, Jannis; Hausmann, Ralf; Bebrivenski, Nikolay; Neuhof, Christian; Detro-Dassen, Silvia; Hautvast, Petra; Benasolo, Carène A; Meents, Jannis; Machtens, Jan-Philipp; Schmalzing, Günther; Lampert, Angelika.
Affiliation
  • Rühlmann AH; Institute of Physiology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Körner J; Institute of Physiology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Hausmann R; Department of Anaesthesiology, Medical Faculty, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Bebrivenski N; Institute of Clinical Pharmacology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Neuhof C; Institute of Clinical Pharmacology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Detro-Dassen S; Institute of Clinical Pharmacology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Hautvast P; Institute of Clinical Pharmacology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Benasolo CA; Institute of Physiology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Meents J; Institute of Clinical Pharmacology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Machtens JP; Forschungszentrum Jülich, Institute of Biological Information Processing (IBI-1), Molekular- und Zellphysiologie, and JARA-HPC, Jülich, Germany.
  • Schmalzing G; Institute of Physiology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
  • Lampert A; Institute of Clinical Pharmacology, Uniklinik RWTH Aachen University, Pauwelsstrasse 30, Aachen, Deutschland, 52074, Germany.
Br J Pharmacol ; 177(19): 4481-4496, 2020 10.
Article in En | MEDLINE | ID: mdl-32663327
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythromelalgia / NAV1.7 Voltage-Gated Sodium Channel Limits: Humans Language: En Journal: Br J Pharmacol Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Erythromelalgia / NAV1.7 Voltage-Gated Sodium Channel Limits: Humans Language: En Journal: Br J Pharmacol Year: 2020 Document type: Article Affiliation country: Country of publication: