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Nasal absorption enhancement of protein drugs independent to their chemical properties in the presence of hyaluronic acid modified with tetraglycine-L-octaarginine.
Tomono, Takumi; Yagi, Haruya; Ukawa, Masami; Ishizaki, Seiya; Miwa, Takahiro; Nonomura, Mao; Igi, Ryoji; Kumagai, Hironori; Miyata, Kohei; Tobita, Etsuo; Kobayashi, Hideo; Sakuma, Shinji.
Affiliation
  • Tomono T; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Yagi H; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Ukawa M; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Ishizaki S; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Miwa T; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Nonomura M; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Igi R; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan.
  • Kumagai H; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan; Life Science Materials Laboratory, ADEKA Co., 7-2-34, Higashiogu, Arakawa-ku, Tokyo 116-8553, Japan.
  • Miyata K; Life Science Materials Laboratory, ADEKA Co., 7-2-34, Higashiogu, Arakawa-ku, Tokyo 116-8553, Japan.
  • Tobita E; Life Science Materials Laboratory, ADEKA Co., 7-2-34, Higashiogu, Arakawa-ku, Tokyo 116-8553, Japan.
  • Kobayashi H; Pharmaceutical and Biomedical Analysis Department, DAIICHI SANKYO RD NOVARE Co., Ltd., 1-16-13, Kitakasai, Edogawa-ku, Tokyo 134-8630, Japan.
  • Sakuma S; Faculty of Pharmaceutical Sciences, Setsunan University, 45-1, Nagaotoge-cho, Hirakata, Osaka 573-0101, Japan. Electronic address: sakuma@pharm.setsunan.ac.jp.
Eur J Pharm Biopharm ; 154: 186-194, 2020 Sep.
Article in En | MEDLINE | ID: mdl-32681963
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Peptides / Nasal Absorption / Hyaluronic Acid Limits: Animals Language: En Journal: Eur J Pharm Biopharm Journal subject: FARMACIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Peptides / Nasal Absorption / Hyaluronic Acid Limits: Animals Language: En Journal: Eur J Pharm Biopharm Journal subject: FARMACIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: