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Development of a chemical probe against NUDT15.
Zhang, Si Min; Desroses, Matthieu; Hagenkort, Anna; Valerie, Nicholas C K; Rehling, Daniel; Carter, Megan; Wallner, Olov; Koolmeister, Tobias; Throup, Adam; Jemth, Ann-Sofie; Almlöf, Ingrid; Loseva, Olga; Lundbäck, Thomas; Axelsson, Hanna; Regmi, Shruti; Sarno, Antonio; Krämer, Andreas; Pudelko, Linda; Bräutigam, Lars; Rasti, Azita; Göttmann, Mona; Wiita, Elisée; Kutzner, Juliane; Schaller, Torsten; Kalderén, Christina; Cázares-Körner, Armando; Page, Brent D G; Krimpenfort, Rosa; Eshtad, Saeed; Altun, Mikael; Rudd, Sean G; Knapp, Stefan; Scobie, Martin; Homan, Evert J; Berglund, Ulrika Warpman; Stenmark, Pål; Helleday, Thomas.
Affiliation
  • Zhang SM; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Desroses M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Hagenkort A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Valerie NCK; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Rehling D; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
  • Carter M; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
  • Wallner O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Koolmeister T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Throup A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Jemth AS; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Almlöf I; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Loseva O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Lundbäck T; Chemical Biology Consortium Sweden, Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Axelsson H; Chemical Biology Consortium Sweden, Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Regmi S; Chemical Biology Consortium Sweden, Science for Life Laboratory, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Sarno A; Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Krämer A; Institute of Pharmaceutical Chemistry, Goethe-University Frankfurt, Frankfurt, Germany.
  • Pudelko L; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Bräutigam L; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Rasti A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Göttmann M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Wiita E; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Kutzner J; Department of Infectious Diseases, University Hospital Heidelberg, Heidelberg, Germany.
  • Schaller T; Department of Infectious Diseases, University Hospital Heidelberg, Heidelberg, Germany.
  • Kalderén C; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Cázares-Körner A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Page BDG; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Krimpenfort R; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
  • Eshtad S; Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Altun M; Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
  • Rudd SG; Science for Life Laboratory, Division of Clinical Physiology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.
  • Knapp S; Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden.
  • Scobie M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Homan EJ; Institute of Pharmaceutical Chemistry, Goethe-University Frankfurt, Frankfurt, Germany.
  • Berglund UW; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Stenmark P; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
  • Helleday T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Nat Chem Biol ; 16(10): 1120-1128, 2020 10.
Article in En | MEDLINE | ID: mdl-32690945

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrophosphatases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2020 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrophosphatases Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2020 Document type: Article Affiliation country: Country of publication: