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Protective Mechanism and Treatment of Neurogenesis in Cerebral Ischemia.
Li, Wanting; Ye, Anqi; Ao, Luyao; Zhou, Lin; Yan, Yunyi; Hu, Yahui; Fang, Weirong; Li, Yunman.
Affiliation
  • Li W; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Ye A; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Ao L; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Zhou L; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Yan Y; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China.
  • Hu Y; Children's Hospital of Nanjing Medical University, # 72 GuangZhou Road, Nanjing, 210008, People's Republic of China. huyahui324@163.com.
  • Fang W; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China. weirongfang@163.com.
  • Li Y; State Key Laboratory of Natural Medicines, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, 210009, People's Republic of China. yunmanlicpu@163.com.
Neurochem Res ; 45(10): 2258-2277, 2020 Oct.
Article in En | MEDLINE | ID: mdl-32794152
ABSTRACT
Stroke is the fifth leading cause of death worldwide and is a main cause of disability in adults. Neither currently marketed drugs nor commonly used treatments can promote nerve repair and neurogenesis after stroke, and the repair of neurons damaged by ischemia has become a research focus. This article reviews several possible mechanisms of stroke and neurogenesis and introduces novel neurogenic agents (fibroblast growth factors, brain-derived neurotrophic factor, purine nucleosides, resveratrol, S-nitrosoglutathione, osteopontin, etc.) as well as other treatments that have shown neuroprotective or neurogenesis-promoting effects.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Ischemia / Neuroprotective Agents / Stroke / Neurogenesis Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Neurochem Res Year: 2020 Document type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Ischemia / Neuroprotective Agents / Stroke / Neurogenesis Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Neurochem Res Year: 2020 Document type: Article