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Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
Van Kolen, Kristof; Malia, Thomas J; Theunis, Clara; Nanjunda, Rupesh; Teplyakov, Alexey; Ernst, Robin; Wu, Sheng-Jiun; Luo, Jinquan; Borgers, Marianne; Vandermeeren, Marc; Bottelbergs, Astrid; Wintmolders, Cindy; Lacy, Eilyn; Maurin, Hervé; Larsen, Peter; Willems, Roland; Van De Casteele, Tom; Triana-Baltzer, Gallen; Slemmon, Randy; Galpern, Wendy; Trojanowski, John Q; Sun, Hong; Mercken, Marc H.
Affiliation
  • Van Kolen K; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Malia TJ; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Theunis C; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Nanjunda R; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Teplyakov A; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Ernst R; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Wu SJ; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Luo J; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Borgers M; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Vandermeeren M; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Bottelbergs A; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Wintmolders C; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Lacy E; Biologics Research, Janssen Research and Development, Spring House, PA, USA.
  • Maurin H; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Larsen P; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Willems R; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
  • Van De Casteele T; Translational Medicine and Early Development Statistics Janssen Research & Development, Beerse, Belgium.
  • Triana-Baltzer G; Neuroscience biomarkers, Janssen Research & Development, La Jolla, CA, USA.
  • Slemmon R; Neuroscience biomarkers, Janssen Research & Development, La Jolla, CA, USA.
  • Galpern W; Neuroscience Experimental medicine, Janssen Research & Development, Titusville, NJ, USA.
  • Trojanowski JQ; University of Pennsylvania Perelman School of Medicine, PA, USA.
  • Sun H; Neuroscience Clinical Development, Janssen Research & Development, Titusville, NJ, USA.
  • Mercken MH; Neuroscience Department, Janssen Research and Development, Beerse, Belgium.
J Alzheimers Dis ; 77(4): 1397-1416, 2020.
Article in En | MEDLINE | ID: mdl-32894244
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Drug Discovery / Antibodies, Monoclonal, Humanized / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / Drug Discovery / Antibodies, Monoclonal, Humanized / Antibodies, Monoclonal Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Alzheimers Dis Journal subject: GERIATRIA / NEUROLOGIA Year: 2020 Document type: Article Affiliation country: Country of publication: