Cost-effectiveness of endoscopic endonasal vs transcranial approaches for olfactory groove meningioma.
Head Neck
; 43(1): 79-88, 2021 01.
Article
in En
| MEDLINE
| ID: mdl-32918329
ABSTRACT
BACKGROUND:
Endoscopic endonasal approaches (EEAs) have been adopted as an alternative to standard transcranial approaches for olfactory groove meningiomas (OGMs). However, the relative cost-effectiveness remains controversial.METHODS:
Cost-utility analysis from a societal perspective comparing EEA vs transcranial approaches for OGM was used in this study. Surgical treatment was modeled using decision analysis, and a Markov model was adopted over a 20-year horizon. Parameters were obtained from literature review. Costs were expressed in 2017 Canadian dollars.RESULTS:
In the base case, EEA was cost-effective compared with transcranial surgery with an incremental cost-effectiveness ratio of $33 523 ($30 475 USD)/QALY. There was a 55% likelihood that EEA was cost-effective at a willingness-to-pay of $50 000/QALY. EEA remained cost-effective at a cerebrospinal fluid leak rate below 60%, gross total resection rate above 25%, and base cost less than $66 174 ($60 158 USD).CONCLUSION:
EEA may be a cost-effective alternative to transcranial approaches for selected OGM.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Meningeal Neoplasms
/
Meningioma
Type of study:
Health_economic_evaluation
/
Prognostic_studies
Aspects:
Patient_preference
Limits:
Humans
Country/Region as subject:
America do norte
Language:
En
Journal:
Head Neck
Journal subject:
NEOPLASIAS
Year:
2021
Document type:
Article
Affiliation country: