Challenges and Opportunities in Implementing Pharmacogenetic Testing in Clinical Settings.
Annu Rev Pharmacol Toxicol
; 61: 65-84, 2021 01 06.
Article
in En
| MEDLINE
| ID: mdl-33006916
ABSTRACT
The clinical implementation of pharmacogenetic biomarkers continues to grow as new genetic variants associated with drug outcomes are discovered and validated. The number of drug labels that contain pharmacogenetic information also continues to expand. Published, peer-reviewed clinical practice guidelines have also been developed to support the implementation of pharmacogenetic tests. Incorporating pharmacogenetic information into health care benefits patients as well as clinicians by improving drug safety and reducing empiricism in drug selection. Barriers to the implementation of pharmacogenetic testing remain. This review explores current pharmacogenetic implementation initiatives with a focus on the challenges of pharmacogenetic implementation and potential opportunities to overcome these challenges.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Pharmacogenomic Testing
Type of study:
Guideline
Limits:
Humans
Language:
En
Journal:
Annu Rev Pharmacol Toxicol
Year:
2021
Document type:
Article