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Synthesis and identification of a novel derivative of salidroside as a selective, competitive inhibitor of monoamine oxidase B with enhanced neuroprotective properties.
Yang, Zelin; Huang, Xin; Lai, Wenfang; Tang, Yuheng; Liu, Junjie; Wang, Yingzheng; Chu, Kedan; Brown, John; Hong, Guizhu.
Affiliation
  • Yang Z; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Huang X; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Lai W; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Tang Y; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Liu J; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Wang Y; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Chu K; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Brown J; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China.
  • Hong G; Centre of Biomedical Research & Development, Fujian University of Traditional Chinese Medicine, No. 1 Huatou Road, Minhou Shangjie, Fuzhou, China. Electronic address: guizhuhong@fjtcm.edu.cn.
Eur J Med Chem ; 209: 112935, 2021 Jan 01.
Article in En | MEDLINE | ID: mdl-33097301
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Reperfusion Injury / Neuroprotective Agents / Glucosides / Monoamine Oxidase / Monoamine Oxidase Inhibitors Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: Eur J Med Chem Year: 2021 Document type: Article Affiliation country: Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Reperfusion Injury / Neuroprotective Agents / Glucosides / Monoamine Oxidase / Monoamine Oxidase Inhibitors Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: Eur J Med Chem Year: 2021 Document type: Article Affiliation country: Country of publication: