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The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.
Huang, Jessie; Lam, Hong; Koziol-White, Cynthia; Limjunyawong, Nathachit; Kim, Donghwa; Kim, Nicholas; Karmacharya, Nikhil; Rajkumar, Premraj; Firer, Danielle; Dalesio, Nicholas M; Jude, Joseph; Kurten, Richard C; Pluznick, Jennifer L; Deshpande, Deepak A; Penn, Raymond B; Liggett, Stephen B; Panettieri, Reynold A; Dong, Xinzhong; An, Steven S.
Affiliation
  • Huang J; Department of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205; hjess@bu.edu sa1510@rbhs.rutgers.edu.
  • Lam H; Department of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205.
  • Koziol-White C; Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, NJ 08854.
  • Limjunyawong N; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
  • Kim D; Solomon H. Snyder Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Kim N; Center for Personalized Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
  • Karmacharya N; Department of Pharmacology, Rutgers-Robert Wood Johnson Medical School, The State University of New Jersey, Piscataway, NJ 08854.
  • Rajkumar P; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
  • Firer D; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Dalesio NM; Department of Environmental Health and Engineering, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205.
  • Jude J; Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Kurten RC; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
  • Pluznick JL; Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205.
  • Deshpande DA; Department of Physiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.
  • Penn RB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, PA 19107.
  • Liggett SB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Center for Translational Medicine, Jane and Leonard Korman Respiratory Institute, Thomas Jefferson University, Philadelphia, PA 19107.
  • Panettieri RA; Center for Personalized Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612.
  • Dong X; Department of Medical Engineering, University of South Florida, Tampa, FL 33612.
  • An SS; Rutgers Institute for Translational Medicine and Science, New Brunswick, NJ 08901.
Proc Natl Acad Sci U S A ; 117(45): 28485-28495, 2020 11 10.
Article in En | MEDLINE | ID: mdl-33097666
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Odorant / Cystic Fibrosis Transmembrane Conductance Regulator / Anoctamin-1 / Muscle, Smooth / Neoplasm Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Document type: Article Country of publication:
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Odorant / Cystic Fibrosis Transmembrane Conductance Regulator / Anoctamin-1 / Muscle, Smooth / Neoplasm Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2020 Document type: Article Country of publication: