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Assessing the safety and pharmacokinetics of the anti-HIV monoclonal antibody CAP256V2LS alone and in combination with VRC07-523LS and PGT121 in South African women: study protocol for the first-in-human CAPRISA 012B phase I clinical trial.
Mahomed, Sharana; Garrett, Nigel; Karim, Quarraisha A; Zuma, Nonhlanhla Y; Capparelli, Edmund; Baxter, Cheryl; Gengiah, Tanuja; Archary, Derseree; Samsunder, Natasha; Doria-Rose, Nicole; Moore, Penny; Williamson, Carolyn; Barouch, Dan H; Fast, Patricia E; Pozzetto, Bruno; Hankins, Catherine; Carlton, Kevin; Ledgerwood, Julie; Morris, Lynn; Mascola, John; Abdool Karim, Salim.
Affiliation
  • Mahomed S; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa Sharana.Mahomed@caprisa.org.
  • Garrett N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Karim QA; Department of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
  • Zuma NY; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Capparelli E; Department of Epidemiology, Mailman School of Public Health, Columba University, New York, New York, USA.
  • Baxter C; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Gengiah T; University of California San Diego, San Diego, California, USA.
  • Archary D; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Samsunder N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Doria-Rose N; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Moore P; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Williamson C; Vaccine Research Center, National Institutes of Health, Bethesda, Maryland, USA.
  • Barouch DH; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Fast PE; National Institute for Communicable Diseases of the National Health Laboratory Services, Johannesburg, South Africa.
  • Pozzetto B; Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
  • Hankins C; National Health Laboratory Services of South Africa, Johannesburg, South Africa.
  • Carlton K; Division of Medical Virology, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.
  • Ledgerwood J; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
  • Morris L; International Aids Vaccine Initiative, New York, New York, USA.
  • Mascola J; GIMAP (EA3064), University of Saint-Etienne/University of Lyon, Saint-Etienne, France.
  • Abdool Karim S; Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
BMJ Open ; 10(11): e042247, 2020 11 26.
Article in En | MEDLINE | ID: mdl-33243815
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Type of study: Clinical_trials / Guideline Aspects: Ethics Limits: Humans Language: En Journal: BMJ Open Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
Add to My VHL
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 Type of study: Clinical_trials / Guideline Aspects: Ethics Limits: Humans Language: En Journal: BMJ Open Year: 2020 Document type: Article Affiliation country: Country of publication: