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The small molecule drug CBL0137 increases the level of DNA damage and the efficacy of radiotherapy for glioblastoma.
Tallman, Miranda M; Zalenski, Abigail A; Deighen, Amanda M; Schrock, Morgan S; Mortach, Sherry; Grubb, Treg M; Kastury, Preetham S; Huntoon, Kristin; Summers, Matthew K; Venere, Monica.
Affiliation
  • Tallman MM; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA; Biomedical Graduate Program, The Ohio State University, Columbus, OH, USA.
  • Zalenski AA; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA; Neuroscience Graduate Program, The Ohio State University, Columbus, OH, USA.
  • Deighen AM; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Schrock MS; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Mortach S; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Grubb TM; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Kastury PS; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Huntoon K; Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
  • Summers MK; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
  • Venere M; Department of Radiation Oncology, James Cancer Hospital and Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA. Electronic address: monica.venere@osumc.edu.
Cancer Lett ; 499: 232-242, 2021 02 28.
Article in En | MEDLINE | ID: mdl-33253788

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Brain Neoplasms / Carbazoles / Glioblastoma / Chemoradiotherapy / Neoplasm Recurrence, Local Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Lett Year: 2021 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Brain Neoplasms / Carbazoles / Glioblastoma / Chemoradiotherapy / Neoplasm Recurrence, Local Limits: Animals / Female / Humans / Male Language: En Journal: Cancer Lett Year: 2021 Document type: Article Affiliation country: Country of publication: