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Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection.
Yao, Hangping; Sun, Yao; Deng, Yong-Qiang; Wang, Nan; Tan, Yongcong; Zhang, Na-Na; Li, Xiao-Feng; Kong, Chao; Xu, Yan-Peng; Chen, Qi; Cao, Tian-Shu; Zhao, Hui; Yan, Xintian; Cao, Lei; Lv, Zhe; Zhu, Dandan; Feng, Rui; Wu, Nanping; Zhang, Wenhai; Hu, Yuhao; Chen, Keda; Zhang, Rong-Rong; Lv, Qingyu; Sun, Shihui; Zhou, Yunhua; Yan, Run; Yang, Guan; Sun, Xinglu; Liu, Chanjuan; Lu, Xiangyun; Cheng, Linfang; Qiu, Hongying; Huang, Xing-Yao; Weng, Tianhao; Shi, Danrong; Jiang, Weidong; Shao, Junbin; Wang, Lei; Zhang, Jie; Jiang, Tao; Lang, Guojun; Qin, Cheng-Feng; Li, Lanjuan; Wang, Xiangxi.
Affiliation
  • Yao H; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
  • Sun Y; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Deng YQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Wang N; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Tan Y; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Zhang NN; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Li XF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Kong C; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Xu YP; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Chen Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Cao TS; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Zhao H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Yan X; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Cao L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Lv Z; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Zhu D; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Feng R; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Wu N; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
  • Zhang W; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Hu Y; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Chen K; Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, 310015, China.
  • Zhang RR; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Lv Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Sun S; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Zhou Y; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Yan R; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Yang G; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 102206, China.
  • Sun X; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Liu C; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China.
  • Lu X; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
  • Cheng L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
  • Qiu H; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Huang XY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Weng T; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
  • Shi D; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China.
  • Jiang W; Shanghai Henlius Biotech, Inc, Shanghai, 200233, China.
  • Shao J; Shanghai ZJ Bio-Tech Co., Ltd., Shanghai, 201114, China.
  • Wang L; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
  • Zhang J; Shanghai ZJ Bio-Tech Co., Ltd., Shanghai, 201114, China.
  • Jiang T; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China.
  • Lang G; Sanyou Biopharmaceuticals (Shanghai) Co., Ltd., Shanghai, 201114, China. guojun.lang@sunyoubio.com.
  • Qin CF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, AMMS, Beijing, 100071, China. qincf@bmi.ac.cn.
  • Li L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310003, China. ljli@zju.edu.cn.
  • Wang X; CAS Key Laboratory of Infection and Immunity, National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. xiangxi@ibp.ac.cn.
Cell Res ; 31(1): 25-36, 2021 01.
Article in En | MEDLINE | ID: mdl-33262452

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Neutralizing / Single-Chain Antibodies / SARS-CoV-2 / COVID-19 / Antibodies, Viral / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Res Year: 2021 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antibodies, Neutralizing / Single-Chain Antibodies / SARS-CoV-2 / COVID-19 / Antibodies, Viral / Epitopes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Res Year: 2021 Document type: Article Affiliation country: