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Discovery of Highly Selective and Potent HDAC3 Inhibitors Based on a 2-Substituted Benzamide Zinc Binding Group.
Liu, Jian; Yu, Younong; Kelly, Joseph; Sha, Deyou; Alhassan, Abdul-Basit; Yu, Wensheng; Maletic, Milana M; Duffy, Joseph L; Klein, Daniel J; Holloway, M Katharine; Carroll, Steve; Howell, Bonnie J; Barnard, Richard J O; Wolkenberg, Scott; Kozlowski, Joseph A.
Affiliation
  • Liu J; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Yu Y; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Kelly J; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Sha D; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Alhassan AB; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Yu W; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Maletic MM; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Duffy JL; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
  • Klein DJ; Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States.
  • Holloway MK; Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States.
  • Carroll S; Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States.
  • Howell BJ; Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States.
  • Barnard RJO; Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States.
  • Wolkenberg S; Merck & Co., Inc., 770 Sumneytown Pike, West Point, Pennsylvania 19486, United States.
  • Kozlowski JA; Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, New Jersey 07033, United States.
ACS Med Chem Lett ; 11(12): 2476-2483, 2020 Dec 10.
Article in En | MEDLINE | ID: mdl-33335670

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2020 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Med Chem Lett Year: 2020 Document type: Article Affiliation country: