Loquat-Inspired Janus Drug Delivery System for Flexible and Robust Tumor Targeting Therapy.
ACS Biomater Sci Eng
; 5(2): 740-747, 2019 Feb 11.
Article
in En
| MEDLINE
| ID: mdl-33405835
ABSTRACT
With the inspiration of the shape of the loquat fruit, here, we developed a similarly shaped Janus carrier. This peculiar gold rod-partially exposed structure not only significantly increased the drug loading capability but also improved its infrared response efficiency. A better effect of drug-photothermal treatment thus could be realized. With the aid of an external 3D printed drug guiding device, this carrier could accurately reach different affected areas. The subsequent infrared triggered multiple tumor therapy, thus, could be conducted in the designated location. The corresponding experimental results demonstrated the reliability, flexibility, and biocompatibility of the proposed drug delivery system for two different tumor targeting treatments.
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1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
ACS Biomater Sci Eng
Year:
2019
Document type:
Article
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