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LMR-101, a novel derivative of propofol, exhibits potent anticonvulsant effects and possibly interacts with a novel target on γ-aminobutyric acid type A receptors.
Zhao, Yi; An, Long; Guo, Shupan; Huang, Xiaoxing; Tian, Huajie; Liu, Li; Chen, Tao; Sun, Xun; Mei, Qibing; Wang, Rutao.
Affiliation
  • Zhao Y; Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai, China.
  • An L; Pharmacology Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, China.
  • Guo S; Department of New Drug Research, Xi'An Libang Pharmaceutical Co, Xi'An, Shaanxi, China.
  • Huang X; Department of New Drug Research, Xi'An Libang Pharmaceutical Co, Xi'An, Shaanxi, China.
  • Tian H; Department of New Drug Research, Xi'An Libang Pharmaceutical Co, Xi'An, Shaanxi, China.
  • Liu L; Pharmacology Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, China.
  • Chen T; Pharmacology Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, China.
  • Sun X; Pharmacology Research Center, Shanghai Institute of Pharmaceutical Industry, Shanghai, China.
  • Mei Q; Department of New Drug Research, Xi'An Libang Pharmaceutical Co, Xi'An, Shaanxi, China.
  • Wang R; Department of Natural Medicine, School of Pharmacy, Fudan University, Shanghai, China.
Epilepsia ; 62(1): 238-249, 2021 01.
Article in En | MEDLINE | ID: mdl-33417274
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Seizures / Status Epilepticus / Propofol / Receptors, GABA-A / Anticonvulsants Type of study: Prognostic_studies Limits: Animals Language: En Journal: Epilepsia Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Seizures / Status Epilepticus / Propofol / Receptors, GABA-A / Anticonvulsants Type of study: Prognostic_studies Limits: Animals Language: En Journal: Epilepsia Year: 2021 Document type: Article Affiliation country: Country of publication: