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The demethylase inhibitor GSK-J4 limits inflammatory colitis by promoting de novo synthesis of retinoic acid in dendritic cells.
Doñas, Cristian; Neira, Jocelyn; Osorio-Barrios, Francisco; Carrasco, Macarena; Fernández, Dominique; Prado, Carolina; Loyola, Alejandra; Pacheco, Rodrigo; Rosemblatt, Mario.
Affiliation
  • Doñas C; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Neira J; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Osorio-Barrios F; Institute of Biomedical Sciences, Faculty of Medicine and Faculty of Life Sciences, Universidad Andres Bello, Av. República 330, Santiago, Chile.
  • Carrasco M; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Fernández D; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Prado C; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Loyola A; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Pacheco R; Fundación Ciencia & Vida, Av. Zañartu 1482, 7780272, Ñuñoa, Santiago, Chile.
  • Rosemblatt M; Universidad San Sebastián, 7510156, Providencia, Santiago, Chile.
Sci Rep ; 11(1): 1342, 2021 01 14.
Article in En | MEDLINE | ID: mdl-33446666
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Tretinoin / Benzazepines / Dendritic Cells / Inflammatory Bowel Diseases / Colitis Limits: Animals Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Tretinoin / Benzazepines / Dendritic Cells / Inflammatory Bowel Diseases / Colitis Limits: Animals Language: En Journal: Sci Rep Year: 2021 Document type: Article Affiliation country: Country of publication: