Use of Pharmacogenomics to Guide Proton Pump Inhibitor Therapy in Clinical Practice.
Dig Dis Sci
; 66(12): 4120-4127, 2021 12.
Article
in En
| MEDLINE
| ID: mdl-33475867
ABSTRACT
Prescribing the right medication, at the right dose, to the right patient is the goal of every physician. Pharmacogenomic information is an emerging tool that can be used to deliver precision medicine. In this review, we discuss the pharmacogenomics of available PPIs, racial differences of CYP2C19 and how PPI pharmacogenomics affects the treatment of common gastrointestinal diseases. We also provide practical guidance on when to order pharmacogenomic testing, which test to order, and how to modify treatment based on published guidelines.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Polymorphism, Genetic
/
Proton Pump Inhibitors
/
Cytochrome P-450 CYP2C19
/
Pharmacogenomic Variants
Type of study:
Guideline
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Dig Dis Sci
Year:
2021
Document type:
Article
Affiliation country: