Coagulation Index and Pregnancy Outcome in Gestational Diabetes Mellitus.

ABSTRACT

BACKGROUND: The purpose of this study was to analyze the coagulation status of gestational diabetes mellitus (GDM) patients in combination with glucose levels and screen out indicators closely related to the severity of GDM and adverse pregnancy outcome. METHODS: The subjects of 110 GDM patients and 100 normal pregnant women were randomly selected. The results of prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen (FIB), D-dimer (D-D), and plaque level test (PLT) in GDM patients and normal pregnant women (comparison group) were analyzed. The study screened out the coagulation indexes of GDM closely related to FPG and then analyzed the correlation between indexes and adverse prognosis. RESULTS: The results of PT were significantly lower in the GDM group. The PT was related to the severity of GDM and adverse pregnancy outcome. CONCLUSIONS: The PT levels of GDM patients in the third trimester can be used as a reliable index for disease and prognosis evaluation.