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CDK2 limits the highly energetic secretory program of mature ß cells by restricting PEP cycle-dependent KATP channel closure.
Sdao, Sophia M; Ho, Thuong; Poudel, Chetan; Foster, Hannah R; De Leon, Elizabeth R; Adams, Melissa T; Lee, Ji-Hyeon; Blum, Barak; Rane, Sushil G; Merrins, Matthew J.
Affiliation
  • Sdao SM; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Ho T; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Poudel C; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Foster HR; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • De Leon ER; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Adams MT; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Lee JH; Cell Growth and Metabolism Section, Diabetes, Endocrinology, and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.
  • Blum B; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
  • Rane SG; Cell Growth and Metabolism Section, Diabetes, Endocrinology, and Obesity Branch, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.
  • Merrins MJ; Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI 53705, USA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53705, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
Cell Rep ; 34(4): 108690, 2021 01 26.
Article in En | MEDLINE | ID: mdl-33503433

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Cyclin-Dependent Kinase 2 / KATP Channels Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2021 Document type: Article Affiliation country:

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Cyclin-Dependent Kinase 2 / KATP Channels Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2021 Document type: Article Affiliation country: