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Physiologically-Based Pharmacokinetic-Pharmacodynamics Model Characterizing CYP2C19 Polymorphisms to Predict Clopidogrel Pharmacokinetics and Its Anti-Platelet Aggregation Effect Following Oral Administration to Coronary Artery Disease Patients With or Without Diabetes.
Xu, Ru-Jun; Kong, Wei-Min; An, Xiao-Fei; Zou, Jian-Jun; Liu, Li; Liu, Xiao-Dong.
Affiliation
  • Xu RJ; Center of Pharmacokinetics and Metabolism, College of Pharmacy, China Pharmaceutical University, Nanjing, China.
  • Kong WM; Center of Pharmacokinetics and Metabolism, College of Pharmacy, China Pharmaceutical University, Nanjing, China.
  • An XF; Department of Endocrinology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinse Medicine, Nanjing, China.
  • Zou JJ; Department of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.
  • Liu L; School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing, China.
  • Liu XD; Center of Pharmacokinetics and Metabolism, College of Pharmacy, China Pharmaceutical University, Nanjing, China.
Front Pharmacol ; 11: 593982, 2020.
Article in En | MEDLINE | ID: mdl-33519456
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Front Pharmacol Year: 2020 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Front Pharmacol Year: 2020 Document type: Article Affiliation country: Country of publication: