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Biocatalytic oxidation of alcohols using galactose oxidase and a manganese(III) activator for the synthesis of islatravir.
Johnson, Heather C; Zhang, Shaoguang; Fryszkowska, Anna; Ruccolo, Serge; Robaire, Sandra A; Klapars, Artis; Patel, Niki R; Whittaker, Aaron M; Huffman, Mark A; Strotman, Neil A.
Affiliation
  • Johnson HC; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Zhang S; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Fryszkowska A; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Ruccolo S; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Robaire SA; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Klapars A; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Patel NR; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Whittaker AM; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Huffman MA; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
  • Strotman NA; Department of Process Research and Development, Merck & Co., Inc., Rahway, NJ 07065, USA. heather.johnson@merck.com.
Org Biomol Chem ; 19(7): 1620-1625, 2021 02 25.
Article in En | MEDLINE | ID: mdl-33533375
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Affiliation country: Country of publication:
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Org Biomol Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2021 Document type: Article Affiliation country: Country of publication: